Christophe Guignabert Selected Research

Autoimmune Diseases (Autoimmune Disease)

1/2022	Driving Role of Interleukin-2-Related Regulatory CD4+ T Cell Deficiency in the Development of Lung Fibrosis and Vascular Remodeling in a Mouse Model of Systemic Sclerosis.
10/2012	Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension.

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Christophe Guignabert Research Topics

Disease

48	Pulmonary Arterial Hypertension 03/2024 - 05/2008
48	Pulmonary Hypertension 05/2023 - 05/2005
25	Hypoxia (Hypoxemia) 04/2024 - 05/2006
24	Vascular Remodeling 09/2023 - 05/2005
17	Inflammation (Inflammations) 12/2023 - 07/2005
13	Fibrosis (Cirrhosis) 04/2024 - 07/2013
8	Disease Progression 04/2024 - 08/2011
8	Hypertrophy 01/2021 - 02/2008
7	Familial Primary Pulmonary Hypertension 07/2021 - 05/2006
7	Neoplasms (Cancer) 10/2019 - 08/2011
6	Systemic Scleroderma (Systemic Sclerosis) 12/2023 - 11/2017
5	Lung Diseases (Lung Disease) 05/2023 - 01/2018
5	Hyperplasia 01/2021 - 05/2005
4	Right Ventricular Hypertrophy 05/2023 - 07/2013
4	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2023 - 11/2017
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2018 - 11/2017
3	Heart Failure 01/2022 - 05/2012
3	Pleural Effusion (Pleural Effusions) 10/2020 - 11/2016
3	Pneumonia (Pneumonitis) 01/2020 - 12/2013
3	Idiopathic Pulmonary Fibrosis 01/2019 - 01/2016
2	Cardiomegaly (Heart Hypertrophy) 04/2024 - 01/2020
2	Obesity 01/2023 - 01/2021
2	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 10/2012
2	Lung Injury 01/2020 - 01/2018
2	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2019 - 01/2018
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2016 - 05/2012
2	Arteritis 08/2015 - 03/2011
1	Portal Hypertension 04/2024
1	Hepatopulmonary Syndrome 04/2024
1	Genetic Predisposition to Disease (Genetic Predisposition) 03/2024
1	Type 2 Diabetes Mellitus (MODY) 05/2023
1	Right Ventricular Dysfunction 01/2023
1	Neuralgia (Stump Neuralgia) 01/2023

Drug/Important Bio-Agent (IBA)

20	MonocrotalineIBA 05/2023 - 05/2005
9	Dasatinib (BMS 354825)FDA Link 03/2024 - 05/2012
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2005
8	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 04/2006
7	CytokinesIBA 01/2023 - 02/2014
7	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 01/2021 - 09/2008
5	LeptinIBA 09/2023 - 10/2012
4	CollagenIBA 08/2023 - 02/2008
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2023 - 03/2011
4	Semaxinib (SU5416)IBA 01/2023 - 01/2018
4	Biomarkers (Surrogate Marker)IBA 01/2023 - 06/2014
4	Platelet-Derived Growth FactorIBA 01/2022 - 11/2017
4	LigandsIBA 10/2021 - 05/2008
4	Therapeutic UsesIBA 01/2020 - 12/2013
4	Tyrosine Kinase InhibitorsIBA 01/2019 - 05/2012
4	Serotonin (5 Hydroxytryptamine)IBA 02/2017 - 04/2006
3	Growth Differentiation Factor 2IBA 04/2024 - 01/2019
3	Vasodilator Agents (Vasodilators)IBA 11/2022 - 02/2017
3	Hormones (Hormone)IBA 01/2021 - 02/2015
3	Imatinib Mesylate (Gleevec)FDA Link 10/2020 - 10/2012
3	Bone Morphogenetic Protein ReceptorsIBA 01/2020 - 09/2009
3	Macrophage Migration-Inhibitory FactorsIBA 01/2020 - 12/2018
3	Bleomycin (Blenoxane)FDA LinkGeneric 12/2018 - 11/2017
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 04/2014 - 03/2009
2	Nerve Growth Factor (NGF)IBA 04/2024 - 08/2015
2	Connexin 43 (Connexin43)IBA 04/2024 - 01/2020
2	Leptin ReceptorsIBA 09/2023 - 01/2016
2	Epoxide HydrolasesIBA 01/2023 - 01/2023
2	Activins (Activin)IBA 01/2023 - 01/2021
2	Activin Receptors (Activin Receptor)IBA 10/2021 - 01/2019
2	Bosentan (Tracleer)FDA Link 01/2021 - 08/2015
2	bosutinibIBA 10/2020 - 11/2016
2	Adenosine (Adenocard)FDA LinkGeneric 01/2020 - 01/2018
2	Type II Bone Morphogenetic Protein Receptors (Bone Morphogenetic Protein Receptor Type II)IBA 01/2020 - 05/2008
2	Endothelin-1 (Endothelin 1)IBA 01/2019 - 08/2015
2	AntibodiesIBA 01/2019 - 11/2017
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 02/2014
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2019 - 08/2011
2	nintedanibIBA 01/2019 - 01/2016
2	PotassiumIBA 10/2018 - 12/2009
2	ambrisentan FDA Link 02/2017 - 08/2015
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 02/2015
2	Interleukin-6 (Interleukin 6)IBA 06/2014 - 04/2014
2	ElastinIBA 03/2011 - 02/2008
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 12/2009 - 05/2005
1	trkA ReceptorIBA 04/2024
1	RNA (Ribonucleic Acid)IBA 12/2023
1	Arsenic Trioxide (Trisenox)FDA Link 12/2023
1	Ubiquitin-Specific ProteasesIBA 09/2023
1	Chimeric Antigen ReceptorsIBA 08/2023
1	Metformin (Glucophage)FDA LinkGeneric 05/2023
1	AMP-Activated Protein KinasesIBA 05/2023
1	Epoprostenol (Prostacyclin)FDA LinkGeneric 05/2023
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2023
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 01/2023
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2023
1	Urea (Carbamide)FDA LinkGeneric 01/2023
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2023
1	pro-brain natriuretic peptide (1-76)IBA 01/2023
1	Epoxy Compounds (Epoxides)IBA 01/2023
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2023
1	ProteomeIBA 01/2023
1	Appetite Depressants (Anorectics)IBA 12/2022

Therapy/Procedure

18	Therapeutics 01/2023 - 12/2013
2	Lung Transplantation 10/2012 - 10/2004
1	Ligation 04/2024
1	Oral Administration 01/2023